| 名稱 | FGFR3 p.Y373C Reference Standard 標準品 |
| 型號 | CBP10550 |
| 報價 |  |
| 特點 | FGFR3 p.Y373C Reference Standard |
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聯(lián)系人：蔣經(jīng)理
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Email： zhangxiangwen@cobioer.com
電話：4008750250
號碼：
手機：18066071954
地址：南京市棲霞區(qū)緯地路9號
Email： zhangxiangwen@cobioer.com
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- 詳細內(nèi)容
CBP10550 | |
| Format | Genomic DNA |
| Description | FGFR3, fibroblast growth factor receptor 3, is a receptor tyrosine kinase activated upon binding of the FGF ligand, which activates RAS-MAPK and PI3K-AKT pathways (PMID: 22508544). Altered function of FGFR3 in cancer may lead to increased cell proliferation and decreased apoptosis (PMID: 22508544) and mutations and fusions are commonly observed in bladder cancer (PMID: 30975452, PMID: 23175443). |
| Technical Data | |
| DNA Change | c.1118A>G |
| AA Change | p.Y373C |
| Mutation type | Missense_Mutation |
| Zygosity | Heterozygous |
| Allelic Frequency | 50% |
| Transcript | NM_000142.5 |
| Cosmic ID | N/A |
| Chr position(GRCh37) | chr4:1806099 |
| Buffer | Tris-EDTA |
| Product Information | |
| Intended Use | Research Use Only |
| Unit Size | 1ug |
| Concentration | Download for COA |
| Purofication | Download for COA |
| DNA electrophoresis | Download for COA |
| Sanger sequencing |
|
| Storage | 4℃ |
| Expiry | 36 months from the date of manufacture |
