| 名稱 | AI-Edigene® NRAS p.G12R Reference Standard Pl |
| 型號 | CBP10522 |
| 報價 |  |
| 特點 | AI-Edigene® NRAS p.G12R Reference Standard Plus |
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聯系人：蔣經理
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Email： zhangxiangwen@cobioer.com
電話：4008750250
號碼：
手機：18066071954
地址：南京市棲霞區緯地路9號
Email： zhangxiangwen@cobioer.com
產品展示 / PRODUCTS
- 詳細內容
CBP10522 | |
| Format | Genomic DNA |
| Description | NRAS G12R is a hotspot mutation that lies within a GTP-binding region of the Nras protein (UniProt.org). G12R has not been characterized, but can be predicted to confer a loss of function on Nras protein based on the effects of HRAS G12R and NRAS G12R, which results in decreased GTPase activity, activation of downstream pathways, and transformation of cultured cells (PMID: 6092966, PMID: 26037647, PMID: 23455880). |
| Technical Data | |
| DNA Change: | c.34G>C |
| AA Change | p.G12R |
| Mutation type | Substitution - Missense |
| Zygosity | Homozygous |
| Allelic Frequency | 100% |
| Transcript | NM_002524.5 |
| Cosmic ID | COSM561 |
| Chr position(GRCh37) | chr1:115258748 |
| Buffer: | Tris-EDTA |
| Product Information | |
| Intended Use | Research Use Only |
| Unit Size | 1ug |
| Concentration | Download for COA |
| Purity | Download for COA |
| DNA electrophoresis | Download for COA |
| Sanger sequencing |
|
| Storage | 4℃ |
| Expiry | 36 months from the date of manufacture |
