| 名稱 | ERBB2 p.V842I Reference Standard 標(biāo)準(zhǔn)品 |
| 型號 | CBP10271 |
| 報價 |  |
| 特點 | ERBB2 p.V842I Reference Standard |
產(chǎn)品搜索
相關(guān)文章
聯(lián)系我們
聯(lián)系人：蔣經(jīng)理
電話：4008750250
號碼：
手機：18066071954
地址：南京市棲霞區(qū)緯地路9號
Email： zhangxiangwen@cobioer.com
電話：4008750250
號碼：
手機：18066071954
地址：南京市棲霞區(qū)緯地路9號
Email： zhangxiangwen@cobioer.com
產(chǎn)品展示 / PRODUCTS
基因檢測標(biāo)準(zhǔn)品 > Mutation > CBP10271ERBB2 p.V842I Reference Standard 標(biāo)準(zhǔn)品
- 詳細內(nèi)容
" _ue_custom_node_="true">
CBP10271 | |
| Format | Genomic DNA |
| Description | ERBB2 (HER2) V842I lies within the protein kinase domain of the Erbb2 (Her2) protein (UniProt.org). V842I results in increased Erbb2 (Her2) activity, downstream Mapk pathway activation, and the ability to transform cells in culture (PMID: 23220880), however in another study, V842I results in similar cell proliferation and viability levels as wild-type Erbb2 (Her2), in two different cell lines (PMID: 29533785). |
| Technical Data | |
| DNA Change | c.2524G>A |
| AA Change | p.V842I |
| Mutation type | Substitution - Missense |
| Zygosity | Heterozygous |
| Allelic Frequency | 50.00% |
| Transcript | ENST00000269571 |
| Cosmic ID | COSM14065 |
| Chr position(GRCh37) | chr17:37881332 |
| Buffer | Tris-EDTA |
| Product Information | |
| Intended Use | Research Use Only |
| Unit Size | 1ug |
| Concentration | Download for COA |
| Purofication | Download for COA |
| DNA electrophoresis | Download for COA |
| Sanger sequencing |
|
| Storage | 4℃ |
| Expiry | 36 months from the date of manufacture |
