| 名稱 | TP53 p.R248Q Reference Standard 標(biāo)準(zhǔn)品 |
| 型號(hào) | CBP10140 |
| 報(bào)價(jià) |  |
| 特點(diǎn) | TP53 p.R248Q Reference Standard |
產(chǎn)品搜索
相關(guān)文章
- IL10及其受體細(xì)胞篩選模型
- 肥胖與腫瘤治療新星靶點(diǎn)——GDF15-GFRAL
- 認(rèn)識(shí)一下北京細(xì)胞庫(kù)的檢測(cè)項(xiàng)目
- Cell Rep：發(fā)現(xiàn)治療乳腺癌轉(zhuǎn)移的重要新靶標(biāo)！
- 選擇本公司的人結(jié)腸癌細(xì)胞株有3個(gè)理由
- 腫瘤細(xì)胞的信息系統(tǒng)的改變特征大揭秘
- 對(duì)ATCC細(xì)胞培養(yǎng)時(shí)的試劑有何要求？
- ATCC細(xì)胞株的特殊性質(zhì)或標(biāo)志必須在整個(gè)培養(yǎng)期間始終存在
- 能量平衡的重要靶點(diǎn)——CRF1R和CRF2R
- PDGFRA靶點(diǎn)藥物細(xì)胞篩選模型
聯(lián)系我們
聯(lián)系人：蔣經(jīng)理
電話：4008750250
號(hào)碼：
手機(jī)：18066071954
地址：南京市棲霞區(qū)緯地路9號(hào)
Email： zhangxiangwen@cobioer.com
電話：4008750250
號(hào)碼：
手機(jī)：18066071954
地址：南京市棲霞區(qū)緯地路9號(hào)
Email： zhangxiangwen@cobioer.com
產(chǎn)品展示 / PRODUCTS
基因檢測(cè)標(biāo)準(zhǔn)品 > Mutation > CBP10140TP53 p.R248Q Reference Standard 標(biāo)準(zhǔn)品
- 詳細(xì)內(nèi)容
" _ue_custom_node_="true">
CBP10140 | |
| Format | Genomic DNA |
| Description | TP53 R248Q is a hotspot mutation that lies within the DNA-binding domain of the Tp53 protein (PMID: 22713868). R248Q results in decreased transactivation of Tp53 targets and interference with wild-type Tp53 transactivation in cell culture, as well as increased Akt activation and enhanced tumor onset and growth in mouse models (PMID: 23538418, PMID: 16861262). |
| Technical Data | |
| DNA Change: | c.743G>A |
| AA Change | p.R248Q |
| Mutation type | Substitution - Missense |
| Zygosity | Homozygous |
| Allelic Frequency | 100% |
| Transcript | ENST00000269305 |
| Cosmic ID | COSM10662 |
| Chr position(GRCh37) | chr17:7577538 |
| Buffer: | Tris-EDTA |
| Product Information | |
| Intended Use | Research Use Only |
| Unit Size | 1ug |
| Concentration | Download for COA |
| Purofication | Download for COA |
| DNA electrophoresis | Download for COA |
| Sanger sequencing |
|
| Storage | 4℃ |
| Expiry | 36 months from the date of manufacture |
會(huì)員_a.png)